| Cross Linker (DVB): | MP |
| Particle Size (mesh): | 200-400 |
| Loading (-Cl: mmol/g): | 1.2-2.0 |
| Macroporous chloromethyl resin is receiving considerable interest as supports in organic synthesis as reagents and catalysts [1-3]. The washing efficiencies of a chromophore and the reaction rates of a classical Merrifield resin [4]. Macroporous chloromethyl resin as a base matrix for solid phase scavengers is superior to the more traditional Merrifield resins when non-swelling solvents like acetonitrile are used. A small library of sulfonamides is generated in high purity as an example [5]. [1] M. Bernard, et al., J. Org. Chem., 1983, 48, 326 [2] H. G. Tang, et al., Polymer, 1993, 34, 2821 [3] H. G. Tang, et al., J.Mol.Catal., 1994, 94, 7 [4] H. Manabu, et al., Bioorg. & Med. Chem. Lett., 1998, 8, 2363 [5] R. B. Nicewonger, et al., Tetrahedron Lett., 2000, 41, 2323 |
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