Macroporous Chloromethyl Resin
(100-200 mesh, 1.2-2.0 mmol/g)

           
Product Catalog # SizePrice (USD) Quantity
$185.00
$464.00
$833.00
Cross Linker (DVB): MP
Particle Size (mesh): 100-200
Loading (-Cl: mmol/g): 1.2-2.0
Macroporous chloromethyl resin is receiving considerable interest as supports in organic synthesis as reagents and catalysts [1-3]. The washing efficiencies of a chromophore and the reaction rates of a classical Merrifield resin [4]. Macroporous chloromethyl resin as a base matrix for solid phase scavengers is superior to the more traditional Merrifield resins when non-swelling solvents like acetonitrile are used. A small library of sulfonamides is generated in high purity as an example [5].
[1] M. Bernard, et al., J. Org. Chem., 1983, 48, 326
[2] H. G. Tang, et al., Polymer, 1993, 34, 2821
[3] H. G. Tang, et al., J.Mol.Catal., 1994, 94, 7
[4] H. Manabu, et al., Bioorg. & Med. Chem. Lett., 1998, 8, 2363
[5] R. B. Nicewonger, et al., Tetrahedron Lett., 2000, 41, 2323