Formyl Resin
(200-400 mesh, 0.6-2.0 mmol/g)

           
Product Catalog # SizePrice (USD) Quantity
$173.00
$316.00
$743.00
$2,376.00
Cross Linker (DVB): 1%
Particle Size (mesh): 200-400
Loading (mmol/g resin): 0.6-2.0
The formyl resin can be used as a support for primary amines, or as a solid-phase support/protecting group for diols [1-2]. Formylpolystyrene has been employed to prepare a range of 2,5 disubstituted tetrahydrofurans via the electrophilic rearrangement of isoxazolines [3]. This resin reacts easily with nucleophiles, such as organolithium reagents, Grignard reagents, and Witting reagents, leading to a variety of modified resin [4].
References
[1] J. M. J. Frechet, et al. , J. Chem. Soc. ,Chem. Commun. , 1975, 225
[2] S. Hanessian., et al. , Carbohyd. Res., 1974, 38, C-15
[3] X. Beebe, et al., J. Am. Chem. Soc., 1992, 114, 10061
[4] M. Cernerud, et al. , Tetrahedron: Asymmetry, 1996, 7, 2863