| Synonym: | N-α-Fmoc-N-ε-4-methyltrityl-L-lysine |
| CAS #: | 167393-62-6 |
| Molecular Formula: | C41H40N2O4 |
| Molecular Weight: | 624.8 |
| Fmoc-Lys(Mtt)-OH is an excellent derivative for the synthesis of branched peptides and peptides modified at the lysine side-chain, and for the construction of templates and multifunctionalized resins for combinatorial synthesis. The side-chain Mtt group can be selectively removed with 1% TFA in DCM or DCM/HFIP/TFE/TES (6.5:2:1:0.5). References 1. K. Barlos, et al., C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283. 2. A. Aletras, et al. (1995) Int. J. Peptide Protein Res., 45, 488. 3. L. Bourel, et al. (2000) J. Peptide Sci., 6, 264. 4. K. Barlos, personal communication. 5. P. Hoogerhout, et al. (1999) J. Peptide Res., 54, 436. 6. C. Park & K. Burgess (2001) J. Comb. Chem., 3, 257. |
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