| Synonym: | Fmoc-L-glutamic acid-γ-[2-(1-sulfonyl-5-naphthyl)-aminoethylamide |
| CAS #: | 193475-66-0 |
| Molecular Formula: | C32H31N3O8S |
| Molecular Weight: | 617.7 |
| Fmoc-Glu(Edans)-OH is a fluorescence-labeled amino acid for preparing fluorescence-quenched peptide substrates. It is used for building block for the synthesis of internally quenched fluorogenic peptide substrates (FRET substrates). The fluorescent group EDANS can be efficiently quenched by the nonfluorescent DABCYL chromophore. References 1. J. W. Drijfhout, et al. in “Peptides, Chemistry, Structure & Biology, Proc. 14th American Peptide Symposium”, P. T. P. Kaumaya & R. S. Hodges (Eds), Kingswinford, Mayflower Scientific Ltd., 1996, pp. 129. 2. L.L.Maggiora et al., J. Med. Chem., 35, 3727 (1992) 3. J.W.Drijfhout et al., Proceedings of the 14th American Peptide Symposium, p. 129, P.T.P.Kaumaya and R.S.Hodges, eds., Mayflower Scientific Ltd. England, (1996). |
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