| Synonym: | AM Resin |
| Cross Linker (DVB): | 1% |
| Particle Size (mesh): | 200-400 |
| Loading (mmol/g): | 1.6-3.0 |
| Aminomethyl polystyrene resin is one of the most widely used functionalized supports for solid-phase synthesis. Many supports can be made by acylating this resin with carboxylic acid-containing linkers using standard amide bond-formation methods. It is also used as a scavenger resin in solution phase synthesis to remove excess acids, alkylating agents and other electrophiles. For the applications of the resin, see ref. [1-7]. References [1] S. D. Bull, et al. Chem. Commun., 2000, 337 [2] L. R. Baxendale & S. V. Ley, Bioorg. Med. Chem. Lett., 2000, 10, 1983 [3] S. V. Ley & A. J. Massi, Chem. Soc., Perkin Trans., 2000, 3645 [4] S. J. Shuttleworth, et al., Bioorg. Med. Chem. Lett., 2000, 10, 2501 [5] M. Li & L. J. Wilson, Tetrahedron Lett., 2001, 42, 1455 [6] J. C. D. Muller-Hartwieg, et al., J. Pept. Sci., 2003, 9, 187 [7] R. M. Kasi & E. B. Coughlin, Organometallics, 2003, 22, 1534 |
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