Products > Resins for Peptide Synthesis > Formyl Resin
Formyl Resin
Catalog # |
Cross Linker (DVB) |
Particle Size
(mesh) |
Loading
(mmol/g resin) |
Price (US $) |
10 g |
25 g |
100 g |
500g |
150601
150602
150603
150604 |
1%
1%
1%
1% |
100-200
100-200
200-400
200-400 |
0.6-2.0
2.0-3.5
0.6-2.0
2.0-3.5 |
173.00
178.00
173.00
178.00 |
316.00
336.00
316.00
336.00 |
743.00
788.00
743.00
788.00 |
2,376.00
2,520.00
2,376.00
2,520.00 |
|
The formyl resin can be used as a support for primary amines, or as a solid-phase support/protecting group for diols [1-2]. Formylpolystyrene has been employed to prepare a range of 2,5 disubstituted tetrahydrofurans via the electrophilic rearrangement of isoxazolines [3]. This resin reacts easily with nucleophiles, such as organolithium reagents, Grignard reagents, and Witting reagents, leading to a variety of modified resin [4].
References
[1] J. M. J. Frechet, et al. , J. Chem. Soc. ,Chem. Commun. , 1975, 225
[2] S. Hanessian., et al. , Carbohyd. Res., 1974, 38, C-15
[3] X. Beebe, et al., J. Am. Chem. Soc., 1992, 114, 10061
[4] M. Cernerud, et al. , Tetrahedron: Asymmetry, 1996, 7, 2863
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