6-TAMRA
(6-Carboxytetramethylrhodamine)
CAS #: |
91809-67-5 |
Molecular
Formula:
|
C25H22N2O5
|
Molecular
Weight:
|
430.5
|
Purity
(HPLC):
|
≥98.00%
|
|
Catalog
# |
Quantity
|
Price
(US $) |
242002
|
100 mg |
200.00 |
500 mg |
400.00 |
1
g |
600.00 |
5
g |
1,800.00 |
6-TAMRA (λex/λem: 541/568nm in DMF or DMSO) is the other purified single isomer of 5(6)-TAMRA. It is predominantly used for oligonucleotide labeling and automated DNA sequencing applications.. It is also used in fluorescence in situ hybridization (FISH).
References
1. Hsu TM, et al. (2001). Genotyping single-nucleotide polymorphisms by the invader assay with dual-color fluorescence polarization detection. Clin Chem 47, 1373-7.
2. Schutz E, et al. (2000). Genotyping of eight thiopurine methyltransferase mutations: three-color multiplexing, two-color/shared anchor and fluorescence-quenching hybridization probe assays based on
thermodynamic nearest-neighbor probe design. Clin Chem 46, 1728-37.
3. Lyttle, M.H., et al., A tetramethyl rhodamine (tamra) phosphoramidite facilitates solid-phase-supported synthesis of 5'-tamra DNA. J Org Chem 2000, 65, 9033-8.
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