Products > Resins for Peptide Synthesis > Sulfonyl Hydrazide Resin





Sulfonyl Hydrazide Resin

Catalog #

Cross Linker (DVB)

Particle Size
(mesh)

Loading
(-N:mmol/g resin)

Price (US $)

25 g

100 g

500g

151909
151910

1%
1%

100-200
200-400

1.0-3.0
1.0-3.0

298.00
298.00

698.00
698.00

2,385.00
2,385.00


The sulfonyl hydrazide resin was generally used as a scavenger to remove the ketone [1]. In a “catch-release” strategy, the ketone solution was directly transferred to a reaction vessel containing Ps-TsNHNH2 resin via cannula. After thionyl chloride cleavage and purification, a series of 1,2,3 – thiadiazdes were prepared with various substituents at 5 position [2].

References

[1] O. Atici, React. & Func. Polym., 1997, 34, 175
[2] Y. H. Hu, et al., J. Org. Chem., 1999, 64, 1049