Products > Resins for Peptide Synthesis > Formyl Resin





Formyl Resin

Catalog #

Cross Linker (DVB)

Particle Size
(mesh)

Loading
(mmol/g resin)

Price (US $)

10 g

25 g

100 g

500g

150601
150602
150603
150604

1%
1%
1%
1%

100-200
100-200
200-400
200-400

0.6-2.0
2.0-3.5
0.6-2.0
2.0-3.5

173.00
178.00
173.00
178.00

316.00
336.00
316.00
336.00

743.00
788.00
743.00
788.00

2,376.00
2,520.00
2,376.00
2,520.00


The formyl resin can be used as a support for primary amines, or as a solid-phase support/protecting group for diols [1-2]. Formylpolystyrene has been employed to prepare a range of 2,5 disubstituted tetrahydrofurans via the electrophilic rearrangement of isoxazolines [3]. This resin reacts easily with nucleophiles, such as organolithium reagents, Grignard reagents, and Witting reagents, leading to a variety of modified resin [4].

References

[1] J. M. J. Frechet, et al. , J. Chem. Soc. ,Chem. Commun. , 1975, 225
[2] S. Hanessian., et al. , Carbohyd. Res., 1974, 38, C-15
[3] X. Beebe, et al., J. Am. Chem. Soc., 1992, 114, 10061
[4] M. Cernerud, et al. , Tetrahedron: Asymmetry, 1996, 7, 2863