Products > Resins for Peptide Synthesis > BHA Resin





BHA Resin
(Benzhydrylamine Hydrochloride Salt Resin)


Catalog #

Cross Linker (DVB)

Particle Size
(mesh)

Loading
(mmol/g)

Price (US $)

25 g

100 g

500g

150201
150202
150203
150204

1%
1%
1%
1%

100-200
100-200
200-400
200-400

0.3-0.8
0.8-1.5
0.3-0.8
0.8-1.5

165.00
172.00
165.00
172.00

377.00
396.00
377.00
396.00

1,218.00
1,291.00
1,218.00
1,291.00



BHA resin has been used as solid carrier for preparation of peptide amides by Boc SPPS [1,2]. Amino acids can be attached to the support using standard amide bond-formation methods. The cleavage of the carboxylic amides from the resin requires strong acids such as trifluoromethane sulfonic acid or HF. These resins are also used as core ones for they are stable to a wide range of acidic and basic conditions.

[1] P. G. Pietta & G. R. Marshall, Chem. Commun. 1970, 650.
[2] G. Mezǒ, et al., Tetrahedron, 1998, 54, 6757
[3] G. Mezǒ, et al., J. Pept. Sci., 1999, 5, 272
[4] G. Mezǒ, et al., Tetrahedron, 1998, 54, 6757