Products > Resins for Peptide Synthesis > Aminomethyl Resin




Aminomethyl Resin
(AM Resin)


Catalog #

Cross Linker (DVB)

Particle Size
(mesh)

Loading
(mmol/g)

Price (US $)

100 g

500 g

1 kg

150101
150102
150103
150104
150105
150106
150107
150108

1%
1%
1%
1%
1%
1%
1%
1%

100-200
100-200
200-400
200-400
30-70
30-70
70-90
70-90

0.4-1.6
1.6-3.0
0.4-1.6
1.6-3.0
0.5-1.0
1.0-2.0
0.5-1.0
1.0-2.0

292.00
310.00
292.00
310.00
292.00
310.00
292.00
310.00

876.00
930.00
876.00
930.00
876.00
930.00
876.00
930.00

1,315.00
1,395.00
1,315.00
1,395.00
1,315.00
1,395.00
1,315.00
1,395.00


Aminomethyl polystyrene resin is one of the most widely used functionalized supports for solid-phase synthesis. Many supports can be made by acylating this resin with carboxylic acid-containing linkers using standard amide bond-formation methods. It is also used as a scavenger resin in solution phase synthesis to remove excess acids, alkylating agents and other electrophiles. For the applications of the resin, see ref. [1-7].

References

[1] S. D. Bull, et al. Chem. Commun., 2000, 337
[2] L. R. Baxendale & S. V. Ley, Bioorg. Med. Chem. Lett., 2000, 10, 1983
[3] S. V. Ley & A. J. Massi, Chem. Soc., Perkin Trans., 2000, 3645
[4] S. J. Shuttleworth, et al., Bioorg. Med. Chem. Lett., 2000, 10, 2501
[5] M. Li & L. J. Wilson, Tetrahedron Lett., 2001, 42, 1455
[6] J. C. D. Muller-Hartwieg, et al., J. Pept. Sci., 2003, 9, 187
[7] R. M. Kasi & E. B. Coughlin, Organometallics, 2003, 22, 1534